Glutathione / GSH

Glutathione | Master Antioxidant for Detoxification & Skin Health Research

Category: Daily Wellness → Antioxidants / Skin Health / Cellular Detox
Keyphrase: Glutathione
Purity: ≥99% (HPLC)

🌿 What is Glutathione?

Glutathione (GSH) is a tripeptide composed of glutamate, cysteine, and glycine. As the most abundant endogenous antioxidant, it helps maintain redox homeostasis, eliminates toxins, and shields cells from oxidative damage. It is vital in protecting mitochondrial function and modulating cellular signaling under stress.

In dermatological research, GSH is investigated for its skin tone balancing effects due to its ability to influence melanogenesis pathways and inhibit tyrosinase activity. These attributes support its use in topical formulations targeting hyperpigmentation and dullness.

🧪 Product Specifications

• Synonyms: GSH, L-Glutathione, Reduced Glutathione

• Molecular Formula: C₁₀H₁₇N₃O₆S

• Molecular Weight: 307.32 g/mol

• Form: Lyophilized powder or aqueous solution

• Purity: ≥99% (HPLC)

🔬 Research Applications

• Oxidative Stress Neutralization:
  Regenerates ascorbate and tocopherol while scavenging reactive oxygen species

• Detox Pathways:
  Supports liver conjugation of harmful xenobiotics and electrophiles

• Skin Brightening Studies:
  Modulates melanin synthesis through thiol-dependent tyrosinase inhibition

• Immunological Models:
  Affects lymphocyte proliferation, cytokine balance, and immune cell activation

• Cognitive and Mitochondrial Support:
  Preserves mitochondrial DNA integrity and delays neurodegeneration

📚 Key Scientific References

1. Redox Biology and Glutathione’s Core Functions
   Free Radic Biol Med, 1999

2. Skin Lightening Potential of GSH
   J Cosmet Dermatol, 2011

3. Immunoregulatory Role of GSH
   Immunol Lett, 2000

🔗 Related Products

• NAD+ – Cofactor in cellular repair and energy cycles

• NMN – Precursor to NAD+ with anti-aging potential

• Alpha-Lipoic Acid – Synergistic antioxidant with mitochondrial targeting

• Vitamin C (Ascorbic Acid) – Enhances glutathione recycling and skin repair

⚠️ For Research Use Only

This product is intended solely for laboratory research, cosmetic formulation development, or preclinical studies. Not intended for therapeutic use or human consumption.