Resmetirom (MGL-3196) – Selective THR-β Agonist | 100mg
Resmetirom (MGL-3196) – Selective THR-β Agonist | 100mg Powder | RUO Grade | BlueBiotech® Research Supply
U.S.-Manufactured SIRT-Targeting Metabolic Research Compound for Liver Fat & Thyroid Pathway Studies
Resmetirom (MGL-3196) is a U.S.-manufactured, orally available selective THR-β agonist developed for use in metabolic and liver disease research. With its targeted action on thyroid hormone receptors, it is a promising agent in nonalcoholic steatohepatitis (NASH), NAFLD, and lipid profile modulation models. Supplied as RUO-grade 100mg high-purity powder. For Research Use Only – Not for human or veterinary use.
| Field Name | Example Value |
|---|---|
| Product Name | Resmetirom (MGL-3196) – Selective THR-β Agonist | 100mg Powder | RUO Grade | BlueBiotech® Research Supply |
| Product Code | BB-RUO-RSMT100 |
| Product Type | Research Compound |
| Category | Metabolic / Liver Disease Research / Thyroid Hormone Pathway |
| Manufacturer | BlueBiotech® Research Facility |
| Appearance | White to off-white crystalline powder |
| Dosage / Units | 100mg per vial |
| Purity | ≥99% (HPLC) |
| Quantity Options | 50mg / 100mg / 250mg |
| Storage | Store at 2–8°C in a sealed, light-protected container |
| Shelf Life | 24 months unopened |
| Packaging | Amber screw-cap vial, tamper-evident sealed |
| Manufacturer Origin | USA – Made in USA |
| Use Classification | RUO – Research Use Only (Not for human therapeutic or diagnostic use) |
| Tags | resmetirom, MGL-3196, THR-β agonist, NASH, NAFLD, thyroid hormone receptor, liver metabolism, RUO, BlueBiotech, made in USA |
⚠️This product is labeled for Research Use Only (RUO). Not for human or veterinary therapeutic use.
See RUO Declaration for more info.
Resmetirom (MGL-3196) – Selective THR-β Agonist | 100mg | RUO Grade | BlueBiotech®
Product Overview
Resmetirom (MGL-3196) is an orally bioavailable, selective thyroid hormone receptor beta (THR-β) agonist, designed to preferentially target hepatic THR-β pathways without activating THR-α receptors in cardiac or skeletal tissue. It has been studied extensively in preclinical and clinical settings for its potential role in regulating lipid metabolism, hepatic steatosis, and non-alcoholic steatohepatitis (NASH).
Manufactured under stringent quality controls by BlueBiotech®, this RUO-grade compound is supplied as 100mg high-purity powder, intended for non-clinical use in metabolic, endocrinological, and liver research.
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Key Features
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✅ Highly selective THR-β receptor agonist
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✅ Investigational use in NASH, NAFLD, and lipid-lowering therapies
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✅ 100mg RUO powder – ≥98% purity (HPLC confirmed)
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✅ No off-target cardiac effects via THR-α activation
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✅ Manufactured in the USA by BlueBiotech®
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✅ Research Use Only – Not for therapeutic or diagnostic use
Specifications
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Compound Name: Resmetirom (MGL-3196)
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CAS Number: 1049870-39-4
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Molecular Formula: C₂₈H₂₆ClNO₆
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Molecular Weight: 507.96 g/mol
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Form: Off-white to pale yellow crystalline powder
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Purity: ≥98% (HPLC)
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Solubility: Soluble in DMSO, ethanol
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Content: 100mg per vial
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Storage: Store at –20°C in a dry, light-protected environment
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Shelf Life: 24 months unopened
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Classification: Research Use Only (RUO)
Research Applications
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Preclinical modeling of NASH and hepatic lipid clearance
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Mechanistic studies of THR-β vs. THR-α selectivity
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Investigation into cholesterol and triglyceride regulation
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Exploration of thyroid hormone analogs in metabolic disease
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Combination studies with PPAR agonists, FXR modulators, or GLP-1 analogs
⚠️ Compliance Statement
This product is designated For Research Use Only (RUO). It is not approved for use in humans or animals and must not be used in any diagnostic, therapeutic, or clinical applications. End-users are responsible for following all applicable institutional and regulatory guidelines.
Tags / Keywords
Resmetirom RUO, MGL-3196 Compound, Selective THR-β Agonist, NASH Research Compound, Fatty Liver Disease Peptide, Thyroid Hormone Receptor Beta Modulator, BlueBiotech Metabolic Tools, RUO Lipid-Lowering Molecule
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Corporate Advantages
High-Purity Standards
Tested for purity and identity. COAs available
for all RUO compounds
Buyer Protection
Protected and discrete fulfillment
available upon request
Research-Grade Support
Dedicated service for labs, clinics, and
compounders handling RUO items.
Lab-Grade Quality Assurance
All compounds are tested for-identity and purity, COAs and supporting documentation are available upon request.
Strict RUO Compliance
All products are labeled for Researd Use Only (RUO), Not intended for human or veterinary therapeutic or diagnostic purposes.
Lab-Grade Quality Assurance
Custom branding.
white-label optionons and formulation assistancee available for eligible research institutions and partners.
Custom R&D & APl Synthesis
We support original
pharmaceutica solutions.custom research projects, and NDC-grade materials-meeting speifica.tions for qualified partners.
Serving Professionals Across the U.S.& Mexico
Trusted by MedSpas, wellness clinics and licensed compounders under licensed compounding relationships.
Secure & Discreet Fulfillment
Cold-chain shipping : private, plain.wrap packaging, and tracking for sensitive RUO materials.
⚠️ All compounds are provided strictly for Research Use Only (RUO). BLUEBIOTECH does not endorse or support clinical, therapeutic, or diagnostic use of its products unless under licensed compounder supervision.