Compounded Tesofensine 10mg Tablets

Compounded Tesofensine 10mg Tablets | Appetite Suppression & Neurogenic Weight Loss Research

Category: Anti-Obesity Research / CNS-Acting Compounds / Neurotransmitter Modulation
Keyphrase: Tesofensine 10mg
Formulation: Compounded Oral Tablets
Purity: ≥99% (HPLC equivalent compound standard)

🧬 What is Tesofensine?

Tesofensine is a triple monoamine reuptake inhibitor (MRI) originally developed as a treatment for neurodegenerative diseases. It works by blocking the reuptake of dopamine, norepinephrine, and serotonin, leading to increased neurotransmitter levels and resulting in significant appetite suppression. In preclinical and clinical studies, Tesofensine has demonstrated powerful weight loss effects, outperforming several current anti-obesity agents.

📌 Product Specifications

• Compound Name: Tesofensine Hydrochloride (HCL)

• Formulation: Oral tablets, compounded – 10mg per unit

• Molecular Formula: C17H23Cl2NO

• Molecular Weight: 328.28 g/mol

• Dosage Form: 30-count bottle (10mg per tablet)

• Purity: Equivalent to ≥99% (HPLC standard)

• Keyphrase: Tesofensine 10mg

🔬 Research Applications

• CNS-mediated appetite suppression and caloric intake reduction

• Obesity and metabolic syndrome model studies

• Comparative evaluation with GLP-1 agonists and bupropion-naltrexone combinations

• Studies on reward behavior and dopamine-driven feeding

• Synergistic investigation with Semaglutide and Cagrilintide in combination therapy models

📚 Clinical & Preclinical References

1. Tesofensine in Obesity: Phase II Study
   Demonstrated ~10% body weight reduction over 24 weeks in overweight adults
   The Lancet, 2008

2. Mechanism of Action in the Hypothalamus
   Enhances dopamine and serotonin signaling in appetite regulation centers
   Neuropsychopharmacology, 2006

3. Synergy with GLP-1 Agonists
   Tesofensine-Cagrilintide dual-action therapy under active exploration
   Diabetes, Obesity and Metabolism, 2022

🔗 Related Research Products

• Cagrilintide – Amylin analog for satiety enhancement

• Compounded Semaglutide – GLP-1 RA for weight management

• Bupropion HCL – Dopamine reuptake modulator in obesity research

⚠️ For Research Use Only

These compounded tablets are formulated for investigational research purposes only. Not for human use. Handle in accordance with institutional biosafety standards.