MOTS-c Peptide 5mg
| Field Name | Example Value |
| Product Name | MOTS-c |
| Product Code | PPT-HK-50-880013 |
| Product Type | Peptide |
| Category | Peptides/Anti-Aging Peptides/Healing & Tissue Repair Peptides |
| Manufacturer | BLUEBIOTECH |
| Appearance | Lyophilized powder |
| Dosage / Units | 5.0mg |
| Purity | ≥ 99% HPLC |
| Storage | Store at 2°C to 8°C. Protect from light and moisture. |
| Shelf Life | 24 months when properly stored |
| Packaging | Sterile vial, vacuum-sealed, labeled for research use only |
| Manufacturer Origin | United States |
| Use Classification | RUO – Research Use Only (Not for human therapeutic use) |
| Tags：MOTS-c Peptide, Mitochondrial Regulation, Anti-Aging, Metabolic Health |
⚠️This product is labeled for Research Use Only (RUO). Not for human or veterinary therapeutic use.
See RUO Declaration for more info.
MOTS-c | Mitochondria-Derived Peptide for Metabolic & Longevity Research
Category: Peptides → Mitochondrial Peptides / Metabolic Regulation
CAS No.: 2014218-67-0
Molecular Formula: C₆₂H₉₆N₁₈O₁₄
Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
Synonyms: Mitochondrial Open Reading Frame of the 12S rRNA Type-c
Purity: ≥99% (HPLC)
Scientific Overview
MOTS-c is a recently discovered mitochondrial-derived peptide (MDP) encoded by the mitochondrial 12S rRNA gene. It functions as a systemic metabolic regulator, capable of translocating to the nucleus and influencing the expression of genes related to insulin sensitivity, adipose metabolism, exercise response, and cellular stress resistance.
MOTS-c represents a novel class of bioactive peptides that bridge mitochondrial signaling and nuclear gene regulation. It is especially prominent in research related to aging, sarcopenia, obesity, type 2 diabetes, and longevity interventions.
Key Research Applications
- Regulation of metabolic homeostasis and insulin signaling pathways
- Enhancement of exercise endurance and skeletal muscle function
- Modulation of mitochondrial stress response (via AMPK pathway)
- Anti-obesity, anti-diabetic, and anti-inflammatory studies
- Investigation of mitochondrial-nuclear communication in aging
Highlighted Research Publications
- Discovery and Functional Characterization
MOTS-c is a mitochondrial-encoded peptide regulating metabolic homeostasis
Cell Metabolism, 2015
→ Identified MOTS-c as a key player in glucose metabolism and insulin action - Anti-Obesity and Insulin Sensitization Effects
MOTS-c reverses diet-induced obesity and improves insulin sensitivity
Aging (Albany NY), 2016 - Exercise Performance and Mitochondrial Adaptation
MOTS-c enhances endurance capacity via skeletal muscle metabolic reprogramming
Nature Communications, 2020 - Aging and Longevity Models
MOTS-c improves lifespan and reduces frailty in aged mice
Nature Aging, 2021
For Research Use Only
This peptide is intended solely for scientific and laboratory research. It is not for human use, therapeutic treatment, or clinical diagnostics. All use must comply with relevant institutional and regulatory standards.
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