ACE-031 – Myostatin Inhibitor Protein | 1mg
ACE-031 – Myostatin Inhibitor Protein | 1mg Lyophilized Powder | RUO Grade | BlueBiotech® Research Supply
sActRIIB-Fc Fusion Protein for Muscle Growth, Cachexia & Muscular Dystrophy Models | Made in USA | Research Use Only
ACE-031 is a recombinant fusion protein consisting of the extracellular domain of human activin receptor type IIB (ActRIIB) linked to an IgG1-Fc. It binds circulating myostatin and related ligands, inhibiting their interaction with muscle receptors. This peptide is under investigation for use in muscle wasting disorders, sarcopenia, and muscular dystrophy research. Supplied as 1mg RUO-grade lyophilized protein. For Research Use Only – Not for human or veterinary use.
Field Name | Example Value |
---|---|
Product Name | ACE-031 – Myostatin Inhibitor Protein | 1mg Lyophilized Powder | RUO Grade | BlueBiotech® Research Supply |
Product Code | BBT-US-30-699810 |
Product Type | Recombinant Protein / Peptide |
Category | Peptides / Muscle Growth / Myostatin Inhibition / Regenerative Biology |
Manufacturer | BlueBiotech® Research Facility |
Appearance | White lyophilized powder |
Dosage / Units | 1mg per vial |
Purity | ≥99% (HPLC) |
Quantity Options | 1mg / 2mg |
Storage | Store at -20°C; avoid repeated freeze/thaw cycles |
Shelf Life | 24 months unopened |
Packaging | RUO-labeled sterile 10R vial, sealed foil pouch |
Manufacturer Origin | USA – Made in USA |
Use Classification | RUO – Research Use Only (Not intended for human or veterinary use) |
Tags | ACE-031, sActRIIB, myostatin inhibitor, muscle growth peptide, muscle wasting, BlueBiotech, RUO, 1mg, made in USA, dystrophy model, fusion protein |
⚠️This product is labeled for Research Use Only (RUO). Not for human or veterinary therapeutic use.
See RUO Declaration for more info.
ACE-031 | ActRIIB-Fc Fusion Protein for Myostatin Inhibition & Muscle Wasting Research
Category: Growth Factors → Myostatin Modulation / Muscle Repair
Keyphrase: ACE-031
Purity: ≥99% (SDS-PAGE)
🧬 What is ACE-031 and How It Works
ACE-031 is a recombinant ActRIIB-Fc fusion protein that functions as a decoy receptor for myostatin (GDF-8) and related ligands like activin A. By intercepting these negative regulators of muscle growth, it prevents them from signaling through native activin receptors—resulting in enhanced skeletal muscle development and reduced atrophy.
📌 Biochemical Properties & Molecular Profile
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Synonyms: Activin Receptor IIB-Fc, Myostatin Trap Protein
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Structure: Recombinant dimeric fusion protein
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Molecular Weight: ~85–90 kDa
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Form: Lyophilized or sterile protein solution
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Purity: ≥99% (SDS-PAGE)
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Keyphrase Use: ACE-031 is intended for laboratory use
🔬 Applications in Myostatin Pathway Research
This myostatin-blocking biologic is widely investigated in models of:
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Muscle-wasting conditions: cachexia, sarcopenia, DMD
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Regenerative therapies to restore lean muscle mass
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Preclinical studies on anabolic signaling and tissue integrity
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Often studied alongside Follistatin, GDF-8 peptide, and IGF-1 analogs
📚 Selected Research Publications
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Muscle Growth via ActRIIB-Fc
Decoy receptor enhances lean mass in animal models
Nature Medicine, 2007 -
DMD Therapeutic Target
Clinical evaluation of ActRIIB-Fc in muscle degeneration
Neuromuscular Disorders, 2013 -
Anti-atrophy Research
Potential benefits in sarcopenia and age-related loss
J Cachexia Sarcopenia Muscle, 2019
🔗 Explore Related Muscle-Building Agents
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Follistatin – Natural myostatin antagonist
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GDF-8 (Myostatin) – Target protein in muscle suppression
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IGF-1 LR3 – Anabolic growth factor for skeletal muscle
⚠️ For Scientific Research Use Only
This product is intended strictly for laboratory and preclinical studies. Not approved for human or veterinary therapeutic use.
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