ACE-031 – Myostatin Inhibitor Protein | 1mg

ACE-031 – Myostatin Inhibitor Protein | 1mg Lyophilized Powder | RUO Grade | BlueBiotech® Research Supply

sActRIIB-Fc Fusion Protein for Muscle Growth, Cachexia & Muscular Dystrophy Models | Made in USA | Research Use Only

ACE-031 is a recombinant fusion protein consisting of the extracellular domain of human activin receptor type IIB (ActRIIB) linked to an IgG1-Fc. It binds circulating myostatin and related ligands, inhibiting their interaction with muscle receptors. This peptide is under investigation for use in muscle wasting disorders, sarcopenia, and muscular dystrophy research. Supplied as 1mg RUO-grade lyophilized protein. For Research Use Only – Not for human or veterinary use.

Field Name Example Value
Product Name ACE-031 – Myostatin Inhibitor Protein | 1mg Lyophilized Powder | RUO Grade | BlueBiotech® Research Supply
Product Code BBT-US-30-699810
Product Type Recombinant Protein / Peptide
Category Peptides / Muscle Growth / Myostatin Inhibition / Regenerative Biology
Manufacturer BlueBiotech® Research Facility
Appearance White lyophilized powder
Dosage / Units 1mg per vial
Purity ≥99% (HPLC)
Quantity Options 1mg / 2mg
Storage Store at -20°C; avoid repeated freeze/thaw cycles
Shelf Life 24 months unopened
Packaging RUO-labeled sterile 10R vial, sealed foil pouch
Manufacturer Origin USA – Made in USA
Use Classification RUO – Research Use Only (Not intended for human or veterinary use)
Tags ACE-031, sActRIIB, myostatin inhibitor, muscle growth peptide, muscle wasting, BlueBiotech, RUO, 1mg, made in USA, dystrophy model, fusion protein

⚠️This product is labeled for Research Use Only (RUO). Not for human or veterinary therapeutic use.
See RUO Declaration for more info.

ACE-031 | ActRIIB-Fc Fusion Protein for Myostatin Inhibition & Muscle Wasting Research

Category: Growth Factors → Myostatin Modulation / Muscle Repair
Keyphrase: ACE-031
Purity: ≥99% (SDS-PAGE)


🧬 What is ACE-031 and How It Works

ACE-031 is a recombinant ActRIIB-Fc fusion protein that functions as a decoy receptor for myostatin (GDF-8) and related ligands like activin A. By intercepting these negative regulators of muscle growth, it prevents them from signaling through native activin receptors—resulting in enhanced skeletal muscle development and reduced atrophy.


📌 Biochemical Properties & Molecular Profile

  • Synonyms: Activin Receptor IIB-Fc, Myostatin Trap Protein

  • Structure: Recombinant dimeric fusion protein

  • Molecular Weight: ~85–90 kDa

  • Form: Lyophilized or sterile protein solution

  • Purity: ≥99% (SDS-PAGE)

  • Keyphrase Use: ACE-031 is intended for laboratory use


🔬 Applications in Myostatin Pathway Research

This myostatin-blocking biologic is widely investigated in models of:

  • Muscle-wasting conditions: cachexia, sarcopenia, DMD

  • Regenerative therapies to restore lean muscle mass

  • Preclinical studies on anabolic signaling and tissue integrity

  • Often studied alongside Follistatin, GDF-8 peptide, and IGF-1 analogs


📚 Selected Research Publications

  1. Muscle Growth via ActRIIB-Fc
    Decoy receptor enhances lean mass in animal models
    Nature Medicine, 2007

  2. DMD Therapeutic Target
    Clinical evaluation of ActRIIB-Fc in muscle degeneration
    Neuromuscular Disorders, 2013

  3. Anti-atrophy Research
    Potential benefits in sarcopenia and age-related loss
    J Cachexia Sarcopenia Muscle, 2019


🔗 Explore Related Muscle-Building Agents


⚠️ For Scientific Research Use Only

This product is intended strictly for laboratory and preclinical studies. Not approved for human or veterinary therapeutic use.

Corporate Advantages

High-Purity Standards

Tested for purity and identity. COAs available
for all RUO compounds

Buyer Protection

Protected and discrete fulfillment
available upon request

Research-Grade Support

Dedicated service for labs, clinics, and
compounders handling RUO items.

Lab-Grade Quality Assurance

All compounds are tested for-identity and purity, COAs and supporting documentation are available upon request.

Strict RUO Compliance

All products are labeled for Researd Use Only (RUO), Not intended for human or veterinary therapeutic or diagnostic purposes.

Lab-Grade Quality Assurance

Custom branding.
white-label optionons and formulation assistancee available for eligible research institutions and partners.

Custom R&D & APl Synthesis

We support original
pharmaceutica solutions.custom research projects, and NDC-grade materials-meeting speifica.tions for qualified partners.

Serving Professionals Across the U.S.& Mexico

Trusted by MedSpas, wellness clinics and licensed compounders under licensed compounding relationships.

Secure & Discreet Fulfillment

Cold-chain shipping : private, plain.wrap packaging, and tracking for sensitive RUO materials.

⚠️ All compounds are provided strictly for Research Use Only (RUO). BLUEBIOTECH does not endorse or support clinical, therapeutic, or diagnostic use of its products unless under licensed compounder supervision.

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