ACE-031
| Field Name | Example Value |
| Product Name | ACE-031 |
| Product Code | BBT-US-30-699810 |
| Product Type | Peptide |
| Category | Peptides |
| Manufacturer | BLUEBIOTECH |
| Appearance | Lyophilized powder |
| Dosage / Units | 1mg |
| Purity | ≥ 99% HPLC |
| Storage | Store at 2°C to 8°C. Protect from light and moisture. |
| Shelf Life | 24 months when properly stored |
| Packaging | Sterile vial, vacuum-sealed, labeled for research use only |
| Manufacturer Origin | United States |
| Use Classification | RUO – Research Use Only (Not for human therapeutic use) |
| Tags：ACE-031 Peptide, Myostatin Inhibitor, Muscle Growth, Tissue Regeneration |
⚠️This product is labeled for Research Use Only (RUO). Not for human or veterinary therapeutic use.
See RUO Declaration for more info.
ACE-031 | ActRIIB-Fc Fusion Protein for Myostatin Inhibition & Muscle Wasting Research
Category: Growth Factors → Myostatin Modulation / Muscle Repair
Keyphrase: ACE-031
Purity: ≥99% (SDS-PAGE)
🧬 What is ACE-031 and How It Works
ACE-031 is a recombinant ActRIIB-Fc fusion protein that functions as a decoy receptor for myostatin (GDF-8) and related ligands like activin A. By intercepting these negative regulators of muscle growth, it prevents them from signaling through native activin receptors—resulting in enhanced skeletal muscle development and reduced atrophy.
📌 Biochemical Properties & Molecular Profile
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Synonyms: Activin Receptor IIB-Fc, Myostatin Trap Protein
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Structure: Recombinant dimeric fusion protein
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Molecular Weight: ~85–90 kDa
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Form: Lyophilized or sterile protein solution
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Purity: ≥99% (SDS-PAGE)
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Keyphrase Use: ACE-031 is intended for laboratory use
🔬 Applications in Myostatin Pathway Research
This myostatin-blocking biologic is widely investigated in models of:
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Muscle-wasting conditions: cachexia, sarcopenia, DMD
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Regenerative therapies to restore lean muscle mass
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Preclinical studies on anabolic signaling and tissue integrity
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Often studied alongside Follistatin, GDF-8 peptide, and IGF-1 analogs
📚 Selected Research Publications
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Muscle Growth via ActRIIB-Fc
Decoy receptor enhances lean mass in animal models
Nature Medicine, 2007 -
DMD Therapeutic Target
Clinical evaluation of ActRIIB-Fc in muscle degeneration
Neuromuscular Disorders, 2013 -
Anti-atrophy Research
Potential benefits in sarcopenia and age-related loss
J Cachexia Sarcopenia Muscle, 2019
🔗 Explore Related Muscle-Building Agents
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Follistatin – Natural myostatin antagonist
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GDF-8 (Myostatin) – Target protein in muscle suppression
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IGF-1 LR3 – Anabolic growth factor for skeletal muscle
⚠️ For Scientific Research Use Only
This product is intended strictly for laboratory and preclinical studies. Not approved for human or veterinary therapeutic use.
Also in GLP-1 Peptides:
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⚠️ All compounds are provided strictly for Research Use Only (RUO). BLUEBIOTECH does not endorse or support clinical, therapeutic, or diagnostic use of its products unless under licensed compounder supervision.