Dermorphin

Field Name Example Value
Product Name Dermorphin
Product Code BBT-US-30-699805
Product Type Peptide
Category Peptides
Manufacturer BLUEBIOTECH
Appearance Lyophilized powder
Dosage / Units 5mg
Purity ≥ 99% HPLC
Storage Store at 2°C to 8°C. Protect from light and moisture.
Shelf Life 24 months when properly stored
Packaging Sterile vial, vacuum-sealed, labeled for research use only
Manufacturer Origin United States
Use Classification RUO – Research Use Only (Not for human therapeutic use)
Tags:Dermorphin Peptide, Opioid Receptor, Pain Research, Anti-Aging

⚠️This product is labeled for Research Use Only (RUO). Not for human or veterinary therapeutic use.
See RUO Declaration for more info.

Dermorphin Peptide | μ-Opioid Receptor Agonist for Pain & CNS Research

Category: Peptides → Neuromodulators / Opioid Receptor Ligands / Pain Studies
Keyphrase: Dermorphin peptide
Purity: ≥99% (HPLC)


🧬 What is Dermorphin?

Dermorphin is a naturally occurring heptapeptide isolated from the skin of South American frogs (Phyllomedusa sauvagei). It is a potent μ-opioid receptor (MOR) agonist, exhibiting 30–40 times higher analgesic activity than morphine in animal models. Its high receptor affinity and resistance to enzymatic degradation make it a key tool in pain modulation, opioid signaling, and addiction pathway studies.

Due to its selectivity for the MOR subtype and ability to cross the blood-brain barrier in certain formulations, Dermorphin is used in both central nervous system pharmacology and experimental neuropathic pain models.


📌 Product Specifications

  • Sequence: H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH₂

  • Synonyms: Dermorphin Acetate, Frog Skin Opioid

  • Molecular Formula: C41H56N8O10

  • Molecular Weight: 812.93 g/mol

  • Form: Lyophilized powder

  • Purity: ≥99% (HPLC)

  • Keyphrase: Dermorphin peptide


🔬 Research Applications

  • Binds selectively to μ-opioid receptors with nanomolar affinity

  • Studied for central analgesic effects and comparison with synthetic opioids

  • Used in research on opioid tolerance, dependence, and neuroadaptive changes

  • Explored as a model compound for peptide-based pain therapy and neuromodulation


📚 Scientific Literature

  1. Discovery of Dermorphin
    Naturally occurring opioid peptide from amphibians with high potency
    European Journal of Pharmacology, 1979

  2. μ-Opioid Selectivity & Efficacy
    Dermorphin shown to have exceptional MOR affinity and prolonged action
    Neuroscience Letters, 1983

  3. Peptide Opioid Mechanisms
    Model compound for opioid receptor research and signal transduction
    Trends in Pharmacological Sciences, 2005


🔗 Related Research Peptides

  • Semax – Non-opioid neuropeptide for pain and cognition

  • PT-141 – Neuromodulator affecting melanocortin and sexual behavior

  • DSIP – Peptide for sleep and stress regulation


⚠️ For Research Use Only

Dermorphin is intended exclusively for scientific and in vitro preclinical research. It is not approved for therapeutic, diagnostic, or veterinary use.

 

Corporate Advantages

High-Purity Standards

Tested for purity and identity. COAs available
for all RUO compounds

Buyer Protection

Protected and discrete fulfillment
available upon request

Research-Grade Support

Dedicated service for labs, clinics, and
compounders handling RUO items.

Lab-Grade Quality Assurance

All compounds are tested for-identity and purity, COAs and supporting documentation are available upon request.

Strict RUO Compliance

All products are labeled for Researd Use Only (RUO), Not intended for human or veterinary therapeutic or diagnostic purposes.

Lab-Grade Quality Assurance

Custom branding.
white-label optionons and formulation assistancee available for eligible research institutions and partners.

Custom R&D & APl Synthesis

We support original
pharmaceutica solutions.custom research projects, and NDC-grade materials-meeting speifica.tions for qualified partners.

Serving Professionals Across the U.S.& Mexico

Trusted by MedSpas, wellness clinics and licensed compounders under licensed compounding relationships.

Secure & Discreet Fulfillment

Cold-chain shipping : private, plain.wrap packaging, and tracking for sensitive RUO materials.

⚠️ All compounds are provided strictly for Research Use Only (RUO). BLUEBIOTECH does not endorse or support clinical, therapeutic, or diagnostic use of its products unless under licensed compounder supervision.

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