Dermorphin
Field Name | Example Value |
Product Name | Dermorphin |
Product Code | BBT-US-30-699805 |
Product Type | Peptide |
Category | Peptides |
Manufacturer | BLUEBIOTECH |
Appearance | Lyophilized powder |
Dosage / Units | 5mg |
Purity | ≥ 99% HPLC |
Storage | Store at 2°C to 8°C. Protect from light and moisture. |
Shelf Life | 24 months when properly stored |
Packaging | Sterile vial, vacuum-sealed, labeled for research use only |
Manufacturer Origin | United States |
Use Classification | RUO – Research Use Only (Not for human therapeutic use) |
Tags:Dermorphin Peptide, Opioid Receptor, Pain Research, Anti-Aging |
⚠️This product is labeled for Research Use Only (RUO). Not for human or veterinary therapeutic use.
See RUO Declaration for more info.
Dermorphin Peptide | μ-Opioid Receptor Agonist for Pain & CNS Research
Category: Peptides → Neuromodulators / Opioid Receptor Ligands / Pain Studies
Keyphrase: Dermorphin peptide
Purity: ≥99% (HPLC)
🧬 What is Dermorphin?
Dermorphin is a naturally occurring heptapeptide isolated from the skin of South American frogs (Phyllomedusa sauvagei). It is a potent μ-opioid receptor (MOR) agonist, exhibiting 30–40 times higher analgesic activity than morphine in animal models. Its high receptor affinity and resistance to enzymatic degradation make it a key tool in pain modulation, opioid signaling, and addiction pathway studies.
Due to its selectivity for the MOR subtype and ability to cross the blood-brain barrier in certain formulations, Dermorphin is used in both central nervous system pharmacology and experimental neuropathic pain models.
📌 Product Specifications
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Sequence: H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH₂
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Synonyms: Dermorphin Acetate, Frog Skin Opioid
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Molecular Formula: C41H56N8O10
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Molecular Weight: 812.93 g/mol
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Form: Lyophilized powder
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Purity: ≥99% (HPLC)
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Keyphrase: Dermorphin peptide
🔬 Research Applications
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Binds selectively to μ-opioid receptors with nanomolar affinity
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Studied for central analgesic effects and comparison with synthetic opioids
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Used in research on opioid tolerance, dependence, and neuroadaptive changes
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Explored as a model compound for peptide-based pain therapy and neuromodulation
📚 Scientific Literature
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Discovery of Dermorphin
Naturally occurring opioid peptide from amphibians with high potency
European Journal of Pharmacology, 1979 -
μ-Opioid Selectivity & Efficacy
Dermorphin shown to have exceptional MOR affinity and prolonged action
Neuroscience Letters, 1983 -
Peptide Opioid Mechanisms
Model compound for opioid receptor research and signal transduction
Trends in Pharmacological Sciences, 2005
🔗 Related Research Peptides
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Semax – Non-opioid neuropeptide for pain and cognition
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PT-141 – Neuromodulator affecting melanocortin and sexual behavior
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DSIP – Peptide for sleep and stress regulation
⚠️ For Research Use Only
Dermorphin is intended exclusively for scientific and in vitro preclinical research. It is not approved for therapeutic, diagnostic, or veterinary use.
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