IGF-1LR3

IGF-1 LR3 | Extended-Action IGF Analog for Muscle Growth & Regenerative Research

Category: Peptides → Growth Factor / Cell Proliferation / Muscle Repair
Purity: ≥99% (HPLC)
Keyphrase: IGF-1 LR3 peptide

🧬 What is IGF-1 LR3?

IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is a modified version of human IGF-1, designed to enhance anabolic effects and resist IGF-binding protein inhibition. This peptide contains a 13-amino acid N-terminal extension and an arginine substitution at position 3, which significantly prolong its half-life and increase receptor affinity.

It is widely used in research involving muscle hypertrophy, cell proliferation, and tissue repair, particularly in models of aging, trauma, or metabolic stress.

📌 Product Specifications

• Sequence: MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA

• Synonyms: Long R3 IGF-1, LR3 IGF-1

• Molecular Formula: C400H625N111O115S9

• Molecular Weight: ~9111 Da

• Purity: ≥99% (HPLC)

🔬 Scientific Research Applications

• Supports muscle regeneration and protein synthesis

• Enhances cell growth and survival via IGF-1 receptor activation

• Bypasses IGFBP inhibition for improved tissue penetration

• Studied in contexts of sarcopenia, injury recovery, and anti-aging

• Works synergistically with MGF, PEG-MGF, and Follistatin

📚 Selected Publications

1. Superior receptor activation in vitro
   Endocrinology, 1995

2. Improved anabolic performance in muscle cells
   Am J Physiol, 2003

3. Circulatory advantages over native IGF-1
   Growth Horm IGF Res, 2000

🔗 Explore Related Peptides

• MGF – Local muscle repair factor

• PEG-MGF – Long-acting muscle regeneration analog

• TB-500 – Systemic tissue healing support

⚠️ For Research Use Only

This compound is strictly intended for scientific research use. It is not for diagnostic, therapeutic, or human administration under any circumstance.