KPV – α-MSH Fragment Anti-Inflammatory Peptide | 10mg

KPV – α-MSH Fragment Anti-Inflammatory Peptide | 10mg | RUO Grade | BlueBiotech®

Product Overview

KPV is a tripeptide fragment derived from the C-terminal sequence of alpha-melanocyte-stimulating hormone (α-MSH), composed of Lys-Pro-Val. Despite its simple structure, KPV retains potent anti-inflammatory activity and is widely studied in models of skin inflammation, inflammatory bowel disease (IBD), and epithelial barrier regulation.

KPV functions as an MC1R receptor agonist, inhibiting the production of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6. It is also known to enhance wound healing, suppress NF-κB signaling, and promote epithelial regeneration, making it a valuable research tool in immunology, dermatology, and gastrointestinal sciences.

Manufactured in the USA by BlueBiotech®, this compound is supplied as 10mg lyophilized powder, with ≥99% purity (HPLC). It is intended strictly For Research Use Only (RUO).

🔬 Learn More:

• PMC – Anti-inflammatory actions of α-MSH and KPV fragment

• PubMed – KPV Peptide in Colitis and Epithelial Repair

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Key Features

• ✅ Tripeptide fragment of α-MSH with high anti-inflammatory potency

• ✅ Modulates NF-κB signaling, cytokine production, and epithelial recovery

• ✅ ≥99% purity (HPLC-confirmed)

• ✅ 10mg lyophilized powder per vial

• ✅ Manufactured in the USA by BlueBiotech®

• ✅ For Research Use Only (RUO)

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Specifications

• Peptide Name: KPV (Lys-Pro-Val)

• CAS Number: 159515-72-1

• Molecular Formula: C17H32N6O4

• Molecular Weight: 384.5 g/mol

• Form: White/off-white lyophilized powder

• Purity: ≥99% (HPLC)

• Solubility: Water, PBS, Acetate buffer

• Storage: –20°C; protect from light and moisture

• Shelf Life: 24 months unopened

• Classification: RUO (Research Use Only)

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Research Applications

• Investigation of inflammatory signaling inhibition (e.g., NF-κB, TNF-α)

• Preclinical models of inflammatory bowel disease (IBD) and colitis

• Studies on cutaneous inflammation, eczema, and psoriasis

• Epithelial healing and barrier function repair

• Anti-inflammatory comparison studies with full-length α-MSH and corticosteroids

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⚠️ Compliance Statement

This product is intended For Research Use Only. It is not approved for human or veterinary use, nor for diagnostic or therapeutic purposes. All users must ensure compliance with relevant institutional and regional regulations.

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Tags / Keywords

KPV Peptide RUO, α-MSH Fragment, Anti-inflammatory Peptide, MC1R Agonist, NF-κB Inhibition, BlueBiotech Research, Epithelial Repair Compound, Colitis Peptide Tool, Wound Healing Research