Compounded Retatrutide 10mg
| Field Name | Example Value |
| Product Name | Compounded Retatrutide |
| Product Code | PPT-HK-50-880010, PPT-HK-50-880011, PPT-HK-15-880012 |
| Product Type | Peptide |
| Category | Peptides / Weight Management |
| Manufacturer | BLUEBIOTECH |
| Appearance | Lyophilized powder |
| Dosage / Units | 5.0mg / 10.0mg / 15.0mg |
| Purity | ≥ 99% HPLC |
| Storage | Store at 2°C to 8°C. Protect from light and moisture. |
| Shelf Life | 24 months when properly stored |
| Packaging | Sterile vial, vacuum-sealed, labeled for research use only |
| Manufacturer Origin | United States |
| Use Classification | RUO – Research Use Only (Not for human therapeutic use) |
| Tags：Compounded Retatrutide Peptide, Weight Management, Metabolic Regulation, Multi-Receptor Agonist |
⚠️This product is labeled for Research Use Only (RUO). Not for human or veterinary therapeutic use.
See RUO Declaration for more info.
Retatrutide | Research Peptide
Category: Peptides → Advanced Weight Management / Triple Agonist Research
CAS No.: 2759026-09-7
Molecular Formula: C₂₀₅H₃₁₈N₅₀O₆₀
Synonyms: LY3437943, Triple Agonist Peptide
Scientific Overview
Retatrutide is an investigational triple hormone receptor agonist targeting GLP-1, GIP, and glucagon receptors, developed by Eli Lilly & Co. for advanced obesity and metabolic disorder research. As the next evolution of incretin-based therapies, Retatrutide integrates appetite suppression, enhanced energy expenditure, and glycemic regulation into a single synthetic peptide—representing a new frontier in weight loss and insulin sensitivity models.
The peptide has demonstrated unprecedented weight loss outcomes in early-phase clinical studies, exceeding those of semaglutide and tirzepatide, and is currently under intense academic and pharmaceutical scrutiny.
Key Mechanistic Targets
- GLP-1R agonism: Enhances insulin secretion and suppresses appetite
- GIPR agonism: Supports β-cell function and glucose homeostasis
- GCGR agonism: Increases energy expenditure and reduces liver fat
- Synergistic effect: Integrates satiety, lipolysis, thermogenesis, and glucose control
Highlighted Research Publications
- Phase 2 Clinical Trial of Retatrutide in Obesity (NEJM 2023)
Triple hormone-receptor agonist Retatrutide in adults with obesity
NEJM, 2023
→ Up to 2% weight reductionafter 48 weeks in non-diabetic adults - Mechanistic Analysis of Triple Agonism
Metabolic reprogramming with GLP-1/GIP/GCGR triple agonists
Cell Metabolism, 2022
→ Describes unique thermogenic and lipolytic pathways activated by Retatrutide - Hepatic Steatosis and Insulin Resistance Research
Retatrutide improves liver fat and insulin sensitivity markers
The Lancet, 2023
→ Significant reductions in liver fat content and HOMA-IR scores - Pharmacokinetics and Safety Profile
A first-in-human study of LY3437943
Clinical Pharmacology in Drug Development, 2022
→ Weekly administration with well-tolerated profile in early-stage trials
For Research Use Only
Retatrutide is a novel investigational compound strictly intended for scientific research purposes only. It is not approved for human use or therapeutic applications. Researchers must follow applicable institutional and legal protocols when handling this substance.
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