Thymosin Alpha-1
Immunomodulatory peptide used in infection, cancer, and vaccine response research
Field Name | Example Value |
Product Name | Thymosin Alpha-1 |
Product Code | BBT-US-30-699791 |
Product Type | Peptide |
Category | Peptides/Anti-Aging Peptides/Healing & Tissue Repair Peptides |
Manufacturer | BLUEBIOTECH |
Appearance | Lyophilized powder |
Dosage / Units | 5mg |
Purity | ≥ 99% HPLC |
Storage | Store at 2°C to 8°C. Protect from light and moisture. |
Shelf Life | 24 months when properly stored |
Packaging | Sterile vial, vacuum-sealed, labeled for research use only |
Manufacturer Origin | United States |
Use Classification | RUO – Research Use Only (Not for human therapeutic use) |
Tags:Thymosin Alpha-1 Peptide, Immune Modulation, Anti-Aging, Immunotherapy |
⚠️This product is labeled for Research Use Only (RUO). Not for human or veterinary therapeutic use.
See RUO Declaration for more info.
Thymosin Alpha-1 (Tα1) | Immune-Activating Peptide for Antiviral & Immuno-Oncology Research
Category: Peptides → Immune Regulation / Antiviral / Tumor Immunology
CAS No.: 62304-98-7
Molecular Formula: C212H350N56O78S
Sequence: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asp-Gly-Glu-Ser-Ala-Ser-Asp-Ala-Gly-Leu-Asp-Arg-Ser-Ala-Gln-Gln-Thr-His
Synonyms: Tα1, Zadaxin (pharmaceutical formulation), Thymalfasin
Purity: ≥99% (HPLC)
Scientific Overview
Thymosin Alpha-1 (Tα1) is a 28-amino acid thymic peptide hormone fragment with well-documented immunoregulatory properties. It enhances T-cell maturation, dendritic cell function, and interferon (IFN) production, making it a critical molecule in innate and adaptive immune activation studies.
Tα1 has been investigated in a wide array of models including chronic viral infections (HBV, HCV, HIV), immunodeficiency syndromes, and cancer immunotherapy, especially for its ability to increase MHC Class I expression, activate natural killer (NK) cells, and synergize with checkpoint inhibitors or chemotherapy.
Key Research Applications
- T-cell and dendritic cell activation in immune response models
- Viral infection research (HBV, HCV, SARS-CoV, HIV, HPV)
- Immunotherapy and cancer vaccine adjuvant research
- Chemotherapy-induced immunosuppression studies
- Sepsis, ARDS, and immune exhaustion models
- Studies on MHC upregulation and IFN signaling enhancement
Highlighted Research Publications
- Antiviral Immunity
Tα1 restores immune function in chronic HBV and HCV patients
Journal of Hepatology, 1999 - Cancer Immunotherapy
Thymosin alpha-1 enhances antitumor immunity and checkpoint inhibitor efficacy
Frontiers in Immunology, 2021 - COVID-19 and Critical Illness Immunity
Tα1 reduces mortality and modulates cytokine storm in severe COVID-19
Clinical Infectious Diseases, 2020 - Immunosenescence & Geriatric Models
Tα1 improves immune surveillance and lymphocyte proliferation in elderly models
Annals of the New York Academy of Sciences, 2007
Product Format & Notes
- Form:Lyophilized peptide powder
- Solubility:Soluble in sterile water or PBS
- Storage:–20°C, dry and protected from light
- Suggested Use:In vitro and in vivo immunology models, viral infection assays, tumor microenvironment studies
For Research Use Only
This peptide is provided strictly for scientific research purposes. It is not approved for human use, therapeutic applications, or diagnostic procedures. Please comply with all institutional and regulatory research guidelines.
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⚠️ All compounds are provided strictly for Research Use Only (RUO). BLUEBIOTECH does not endorse or support clinical, therapeutic, or diagnostic use of its products unless under licensed compounder supervision.